Base-promoted transformation of 2-C(O)R-1,8-bis(dimethylamino)naphthalenes into benzo[g]indole derivatives

Jun 5, 2015·

Kachalkina

G. S. Borodkin

Prof. Alexander Pozharskii

Corresponding author

Dr. Alexander Antonov

I. G. Borodkina

Y. F. Maltsev

E. A. Filatova

A. Filarowski

V. A. Ozeryanskii

· 0 min read

DOI

Abstract

1,8-Bis(dimethylamino)naphthalenes bearing 2-positioned trifluoroacetyl or ethoxycarbonyl group on treatment with 2-lithio-1,8-bis-dimethylamino)naphthalene undergo base-promoted transformation into benzo[g]indole derivatives in small to moderate yield, representing previously unknown mode of the pyrrole ring closure which proceeds via deprotonation of the NMe group.

Publication

Mendeleev Commun. 2015, 25, 182–184

Last updated on Jun 5, 2015

Authors

Kachalkina

Authors

G. S. Borodkin

Authors

Prof. Alexander Pozharskii

1938-2025

Prof. Pozharskii was not only my PhD supervisor, but he was a beacon in the scientific world for me. He taught me how to properly plan an experiment, how to write research papers, how to supervise students, how to make grant applications, and how to give lectures. I am who I am today thanks to Prof. Pozharskii and his contribution to me.